Simpsonville's Best Pizza [Updated 2025]

Simpsonville's Best Pizza [Updated 2025]
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After countless taste tests and late-night pizza cravings, I've narrowed down the absolute best spots for a slice in this charming little town. I’ve scoured through 12 top locations, each offering their unique spin on this beloved classic. From crispy crusts to mouthwatering toppings, I’ve tasted it all so you don’t have to!

You can trust my palate—the quest for the perfect pizza has become a delicious obsession. Whether you're a cheese lover, a veggie enthusiast, or a meat aficionado, I’ve got recommendations that’ll make your taste buds sing. So grab a napkin and get ready to uncover the pizza treasures that Simpsonville has to offer!


The Slice

The Slice
🗺️ 134 S Main St, Simpsonville, SC 29681
☎️ 864-757-9330
🌐 Website
Sunday: 11 AM–9 PM
Monday: 11:30 AM–9 PM
Tuesday: 11:30 AM–9 PM
Wednesday: 11:30 AM–9 PM
Thursday: 11:30 AM–9 PM
Friday: 11:30 AM–10 PM
Saturday: 11 AM–10 PM
Highlights
Great pizza worth the wait
Friendly and welcoming staff
Perfectly cooked and flavorful pies
Crispy yet soft crust
Family-like atmosphere

The Slice in Simpsonville is an absolute gem that has quickly claimed a spot in my pizza-loving heart. As I walked in, I was greeted by the friendly and welcoming staff, instantly making me feel at home. The atmosphere had a delightful family-like vibe that added to the overall experience.

Now, let’s talk about the pizza. I ordered a classic Margherita, and I couldn't have been more pleased. The pies here are definitely worth the wait; the moment they arrived at my table, I was captivated by the aroma. The crust was a perfect balance—crispy yet soft, creating an impeccable base for the fresh toppings. Each bite was a burst of flavor, where the simplicity of the sauce complemented the gooey cheese beautifully.

What I loved most was the attention to detail in every aspect of the pizza. It’s evident that they take pride in their craft. So, if you're on the hunt for a quality slice, look no further than The Slice. This spot not only delivers delicious pizza but also leaves you with a sense of community—proving that great food really can bring people together! 🍕

You might also want to check out the best breakfast restaurants in Charleston.

Anthony's Pizzeria

Anthony's Pizzeria
🗺️ 655 Fairview Rd Ste A, Simpsonville, SC 29680
☎️ 864-228-9677
🌐 Website
Sunday: Closed
Monday: 11 AM–8:30 PM
Tuesday: 11 AM–8:30 PM
Wednesday: 11 AM–8:30 PM
Thursday: 11 AM–8:30 PM
Friday: 11 AM–9 PM
Saturday: 11 AM–8:30 PM
Highlights
Delicious wings available
Attentive and sweet service
Amazing aroma upon entry
Consistently delicious food
Picky eater approved pizza

Anthony's Pizzeria in Simpsonville truly delivers an experience that delights on multiple levels! As I stepped through the door, the amazing aroma instantly enveloped me, promising a memorable meal. The ambiance was inviting, and the decor made me feel right at home.

The attentive and sweet service I received only enhanced my visit. The staff was genuinely welcoming and made me feel like a valued guest. Now, let's get to the star of the show: the pizza! Their offerings are nothing short of spectacular, and as a self-proclaimed picky eater, I can confidently say their pies hit the mark. Each slice is crafted with care, featuring a crisp yet chewy crust and a balance of flavors that I found simply irresistible.

And while you're there, don’t overlook the delicious wings — they are the perfect companion to your pizza and definitely worth saving room for! Overall, my visit to Anthony's left me more than satisfied. I can’t wait to return and savor more of what this pizzeria has to offer. It's spots like these that make Simpsonville a pizza lover's paradise!

You might also want to check out the best restaurants in Spartanburg.

Napoli Pizzeria

Napoli Pizzeria
🗺️ 2531 Woodruff Rd, Simpsonville, SC 29681
☎️ 864-627-0019
🌐 Website
Sunday: Closed
Monday: Closed
Tuesday: 11 AM–9 PM
Wednesday: 11 AM–9 PM
Thursday: 11 AM–9 PM
Friday: 11 AM–9:30 PM
Saturday: 11 AM–9:30 PM
Highlights
Amazing food
Great service
Delicious menu options
Unique daily soups
Inviting ambiance

Napoli Pizzeria in Simpsonville truly elevates the pizza dining experience! From the moment I stepped inside, I was greeted by an inviting ambiance that instantly made me feel at home. The warmth of the decor complements the delicious aroma wafting through the air—a promising start to any meal.

The service here is nothing short of exceptional. The staff is attentive and genuinely passionate about the food they serve, a quality that makes a big difference. I couldn't resist diving into their extensive menu, featuring not only their signature pizzas but also unique daily soups that are worth trying!

When it comes to the pizza itself, Napoli doesn’t disappoint. The crust strikes a perfect balance—crispy on the outside while remaining soft and chewy on the inside. The toppings are fresh and generous without overwhelming the palate. Each bite bursts with flavor, leaving me wanting more.

In a town filled with pizza joints, Napoli Pizzeria stands out, delivering amazing food and delightful service. If you’re in Simpsonville and craving a slice, this spot is a must-try. Trust me; your taste buds will thank you!

You might also want to check out the best pizza in Myrtle Beach.

The Slice 2.0 Fountain Inn

The Slice 2.0 Fountain Inn
🗺️ 119 N Main St, Fountain Inn, SC 29644
☎️ 864-408-9399
🌐 Website
Sunday: 11:30 AM–8 PM
Monday: 11:30 AM–8 PM
Tuesday: 11:30 AM–8 PM
Wednesday: 11:30 AM–8 PM
Thursday: 11:30 AM–8 PM
Friday: 11:30 AM–9 PM
Saturday: 11:30 AM–9 PM
Highlights
Northern-style pizza
Crispy, flavorful crust
Generous pepperoni slices
Convenient grab and go
Friendly and responsive staff

The Slice 2.0 Fountain Inn is a hidden gem that truly captures what pizza is all about! As soon as I walked in, I was greeted by a friendly and responsive staff who made me feel right at home. Their Northern-style pizza is a delightful twist that elevates the traditional pie experience.

What particularly stood out was the crispy, flavorful crust that perfectly cradles the toppings, adding an excellent textural contrast to each delightful bite. I opted for a classic pepperoni, and let me tell you, the slices were generous—a necessary characteristic for any true pizza aficionado! Each piece was sizzling with just the right amount of spice, tantalizing my taste buds with every chew.

Another plus is the convenient grab-and-go option, making it a perfect stop for those busy evenings when you crave deliciousness but have a schedule to keep. If you’re in the area and on the hunt for a pizza experience that marries quality with convenience, then The Slice 2.0 should be at the top of your list. Whether you dine in or take it out, this spot serves up a pizza that’s bound to have you coming back for more!

You might also want to check out the best pizza in North Myrtle Beach.

1885 Taproom

1885 Taproom
🗺️ 104A E Curtis St, Simpsonville, SC 29681
☎️ 864-962-3300
🌐 Website
Sunday: 12–6 PM
Monday: Closed
Tuesday: 3–9 PM
Wednesday: 3–9 PM
Thursday: 3–11 PM
Friday: 12–11 PM
Saturday: 12–11 PM
Highlights
Nice rustic atmosphere
30 craft beers on tap
Prompt and friendly service
Great food portion sizes
Outdoor seating available

Stepping into 1885 Taproom is like being transported to a cozy, rustic haven—its ambiance whispers of wood and warmth, making it a perfect spot to unwind. As I settled in, I scanned the impressive selection of 30 craft beers on tap. It’s hard to resist pairing a cold brew with your meal, and I was eager to dive into their pizza offerings.

Now, let’s talk pizza! The options are generous, not just in variety but also in portion sizes, ensuring no one leaves hungry. I opted for their margherita pizza, and let me tell you, it was a delightful symphony of flavors. The crust was perfectly crispy yet chewy, and the fresh basil added an herbaceous note that paired beautifully with the tangy tomato sauce and gooey mozzarella cheese.

What truly stole the show, though, was the prompt and friendly service. My server was attentive, checking in just the right amount and making sure everything was to my liking. The outdoor seating available makes it a great choice for those lovely Simpsonville evenings. If you're seeking a combination of great pizza and a fantastic atmosphere, 1885 Taproom is simply a must-visit.

You might also want to check out the best cafe in Charleston.

BOVA Pizza

BOVA Pizza
🗺️ 2700 Woodruff Rd, Simpsonville, SC 29681
☎️ 864-234-1315
🌐 Website
Sunday: Closed
Monday: 11 AM–10 PM
Tuesday: 11 AM–10 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–10 PM
Saturday: 11 AM–10 PM
Highlights
Delicious and fresh pizza
Best pizza in South Carolina
Extensive menu options
Patio seating available
Friendly atmosphere

Review of BOVA Pizza

Upon stepping into BOVA Pizza, I was immediately welcomed by a vibrant atmosphere that felt both cozy and invigorating. I knew I was in for a treat when I caught a whiff of delicious, freshly baked dough that spoke to my pizza-loving soul. The extensive menu had me intrigued, with options catering to every craving imaginable.

I decided to try their signature pie, which they boldly declare to be the best pizza in South Carolina. Each slice was a perfectly balanced symphony of flavors, with a crisp yet chewy crust that held up beautifully to generous toppings. The freshness of the ingredients was evident, as they used only the highest quality vegetables and meats.

What truly set BOVA apart, however, was the friendly staff and inviting patio seating. Whether you’re grabbing a casual dinner with friends or enjoying a family night out, the ambiance here is top-notch. It’s no wonder this gem has become a favorite in Simpsonville.

If you're ever in town, treat yourself to some pizza paradise at BOVA. You won't be disappointed! 🍕

You might also want to check out the best breakfast in North Myrtle Beach.

Warehouse at Vaughns

Warehouse at Vaughns
🗺️ 109 W Trade St, Simpsonville, SC 29681
🌐 Website
Sunday: 11:30 AM–8 PM
Monday: 11:30 AM–8 PM
Tuesday: 11:30 AM–10 PM
Wednesday: 11:30 AM–10 PM
Thursday: 11:30 AM–10 PM
Friday: 11:30 AM–11 PM
Saturday: 11 AM–11 PM
Highlights
Amazing food concept
Friendly and professional staff
Lovely outdoor market
Varies in wait and parking
Avoid the sushi bar

Warehouse at Vaughns has become a haven for pizza lovers in Simpsonville. Nestled in a vibrant outdoor market, this charming spot serves up an amazing food concept that goes beyond your average slice. As soon as I walked in, the friendly and professional staff made me feel right at home. Their enthusiasm for their craft was palpable, and it enhanced my overall experience.

I decided to try their signature pizza, and let me tell you, it was a delightful spectacle! The crust was a perfect balance of crispy and chewy, topped with a delightful symphony of fresh ingredients. Every bite was a celebration of flavor!

One aspect I noted was the varies in wait and parking situation. Busy times can lead to a bit of a wait, so be prepared for that. However, the quality of the pizza makes it well worth the time. Just a heads-up: I would recommend skipping the sushi bar here; the pizza is truly where they shine!

In conclusion, if you’re looking for a slice of happiness while enjoying the lovely outdoor market atmosphere, Warehouse at Vaughns is an absolute must-visit for anyone searching for the best pizza in Simpsonville!

You might also want to check out the best ice cream in Myrtle Beach.

Shortfields Simpsonville

Shortfields Simpsonville
🗺️ 111 N Main St, Simpsonville, SC 29681
☎️ 864-757-8228
🌐 Website
Sunday: 11 AM–2 PM
Monday: 11 AM–9 PM
Tuesday: 11 AM–9 PM
Wednesday: 11 AM–9 PM
Thursday: 11 AM–9 PM
Friday: 11 AM–10 PM
Saturday: 11 AM–9 PM
Highlights
Family-friendly atmosphere
Good quality food options
Ample free parking available
Artful furnishings
Good value for money

Having explored the pizza scene in Simpsonville, I found myself stepping into Shortfields Simpsonville—a place that's as inviting as it is delicious. The family-friendly atmosphere immediately caught my attention, with cheerful décor and artful furnishings that make you feel right at home. It’s a perfect spot for gathering loved ones and sharing great food.

As I browsed the menu, I was pleasantly surprised by the good quality food options available. The pizza I ordered was a delightful explosion of flavors, boasting a perfectly crisp crust and generous toppings that didn’t skimp on freshness. I found it truly delivered on value, with a taste that made every bite worth it.

In addition to the fantastic cuisine, Shortfields also offers ample free parking, making it convenient for those busy evenings when you want to indulge without the hassle. If you’re looking for something to satisfy your pizza cravings without breaking the bank, this spot has you covered. Overall, my visit was nothing short of delightful, confirming my belief that Shortfields Simpsonville is a contender for the best pizza in town! 🍕

You might also want to check out the best burgers in Greenville.

Milano Pizzeria & Restaurant

Milano Pizzeria & Restaurant
🗺️ 633 SE Main St, Simpsonville, SC 29681
☎️ 864-962-0777
🌐 Website
Sunday: 11 AM–10 PM
Monday: Closed
Tuesday: 11 AM–9:30 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–10 PM
Saturday: 11 AM–10 PM

At Milano Pizzeria & Restaurant, I discovered a slice of heaven! The thin crust was perfectly crispy, supporting a vibrant symphony of flavors from their house-made tomato sauce. Each bite of the pepperoni was a delightful kick, infused with just the right amount of spice. Their generous cheese pull was a gooey masterpiece that had me coming back for more. The cozy ambiance made me feel at home, while the friendly staff added a sprinkle of joy to the visit. If you're in Simpsonville and craving pizza that dances on your taste buds, Milano is a must-visit! 🍕

You might also want to check out the best hamburger in Greenville.

The Bus Pizza

The Bus Pizza
🗺️ 200 S Main St Suite C, Simpsonville, SC 29681
☎️ 864-395-8916
🌐 Website
Sunday: 11 AM–8 PM
Monday: Closed
Tuesday: 11 AM–2 PM
Tuesday: 4:30–9 PM
Wednesday: 11 AM–2 PM
Wednesday: 4:30–9 PM
Thursday: 11 AM–2 PM
Thursday: 4:30–9 PM
Friday: 11 AM–2 PM
Friday: 4:30–10 PM
Saturday: 11 AM–2 PM
Saturday: 4:30–10 PM

During my visit to The Bus Pizza, I was greeted by a warm and vibrant atmosphere that instantly set a fun tone. The menu boasts an array of creative pies, but I opted for their signature pepperoni and jalapeño combo. The crust was perfectly crispy and slightly chewy—an ideal canvas for a rich tomato sauce that danced with flavor. The balance of spice and savory goodness made each bite a delight! The quirky bus interior adds character to the dining experience, reminding you that great pizza often comes with a side of fun. Definitely a must-visit for pizza lovers in Simpsonville!

You might also want to check out the best restaurants in Kiawah Island.

Full House Sportzaria

Full House Sportzaria
🗺️ 404 Harrison Bridge Rd A, Simpsonville, SC 29680
☎️ 864-757-8396
🌐 Website
Sunday: 12–9 PM
Monday: 12–10 PM
Tuesday: 12–10 PM
Wednesday: 12–10 PM
Thursday: 12–10 PM
Friday: 12–11 PM
Saturday: 12–11 PM

At Full House Sportzaria, every bite feels like a winning play! The crust is perfectly golden and crisp, supporting a delightful array of toppings that burst with flavor. Their signature pepperoni pizza is a must-try—each slice oozes gooey cheese and zesty tomato sauce. The lively atmosphere, complete with games and screens for sports fans, makes it an ideal spot for casual gatherings. The staff is welcoming, adding a personal touch to the experience. If you're in the mood for pizza perfection, this gem is a grand slam that shouldn't be missed in Simpsonville!

You might also want to check out the best lunch in Myrtle Beach.

Hot Pie (Frank's Pizza)

Hot Pie (Frank's Pizza)
🗺️ 1122 Fairview Rd, Simpsonville, SC 29680
☎️ 864-408-9492
Sunday: 11 AM–9 PM
Monday: Closed
Tuesday: 10 AM–9 PM
Wednesday: 10 AM–9 PM
Thursday: 10 AM–9 PM
Friday: 10 AM–9:30 PM
Saturday: 10 AM–9:30 PM

During my visit to Hot Pie (Frank's Pizza), I was greeted by the inviting aroma of freshly baked dough and tantalizing toppings. I opted for their signature pepperoni pizza, which was a delightful blend of crispy crust, rich sauce, and generous cheese. Each slice practically sung with flavor, making it hard to stop at just one! The lively decor and friendly staff added to the overall experience, creating a perfect atmosphere for pizza lovers. If you're seeking tantalizing options in Simpsonville, Hot Pie certainly deserves a spot on your list—it's a slice of heaven you won’t want to miss!

You might also want to check out the best restaurant in Greer.

Emily JohnsonE
WRITTEN BY

Emily Johnson

Emily Johnson is an avid storyteller and passionate advocate for Charleston, South Carolina, where she explores the city's rich history, vibrant culture, and hidden gems. Through her writing, she invites readers to experience the charm and beauty of the Lowcountry, one captivating article at a time.Read more

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Food tour map
Charleston Secret Guide 🤫

Charleston Hot List 🔥

Get our exclusive guide to the top spots in Charleston! This guide includes:

  • Top 7 must-visit culinary destinations
  • Optimized 3-stop food tour route with a map
  • Expert insider tip for each location (when to go/what to order)
  • QR codes for easy navigation
  • More secret spots in your inbox every week