The Absolute Best Pizza in Downtown Greenville [Updated 2025]

As I dove into the vibrant food scene here, I knew I had to tackle one of the most beloved staples: pizza. After tasting my way through 12 top spots—each with its own unique twist—I’ve gathered some delicious insights that are sure to satisfy your cravings.

With my palate honed from years of culinary adventures, I’ve got the scoop on where to find the cheesiest slices, the crispiest crusts, and those secret sauce recipes that keep you coming back for more. Whether you’re a local or just passing through, I promise you’ll want to make a pit stop at these pizza joints. Let’s dig in!

Myles Pizza Pub

Highlights
Amazing gluten-free options
Friendly and welcoming staff
Delicious cheesy pizza
Cozy atmosphere for dates
Homemade ingredients used

Myles Pizza Pub in Downtown Greenville is a delightful haven for pizza lovers! As soon as I stepped inside, I was greeted by the friendly and welcoming staff, creating an atmosphere that felt instantly cozy and inviting — perfect for a casual date night or a fun gathering with friends.

Now, let’s talk about what really matters: the pizza! I had the pleasure of indulging in their cheesy delight, piled high with homemade ingredients that burst with flavor. Each bite was a symphony of gooey goodness, making it evident that Myles takes pride in their craft. For those with dietary restrictions, their amazing gluten-free options ensure that everyone can join in on the pizza party without compromise.

The atmosphere is filled with laughter and warmth, reflecting the community spirit that Downtown Greenville is known for. With so many delicious offerings, it’s easy to see why Myles Pizza Pub is quickly becoming a local favorite. If you’re looking for a spot where you can enjoy honest, heartfelt pizza, look no further; this place has it all!

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Tacozzini

Highlights
Great service and personable staff
Delicious food with unique flavors
Family-friendly atmosphere
Enjoyable live music
Tasty BBQ with pineapple salsa

Tacozzini: A Slice of Flavor in Downtown Greenville

As I stepped into Tacozzini, I was immediately greeted by the friendly staff, radiating warmth and eagerness to help. It felt like a cheerful neighborhood spot that made you feel right at home. The atmosphere was vibrant, perfect for families, couples, or anyone looking to enjoy a slice—perhaps more than one!

What truly sets Tacozzini apart is their unique flavor profile. I indulged in their specialty pizza, expertly topped with BBQ and a tantalizing pineapple salsa. The explosion of sweet and savory was nothing short of magical, a delightful dance on my taste buds. Each bite was perfectly balanced, showcasing a creativity that often eludes traditional pizzerias.

To top off the experience, they had live music that enhanced the ambiance without overpowering conversation. It created a jovial backdrop, making my visit feel like a celebration rather than just another meal.

In all honesty, Tacozzini is more than a pizza place; it’s a cozy gathering spot in the heart of Downtown Greenville. If you find yourself in the area, do yourself a favor and savor a slice of their innovation—you won't regret it!

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Indaco

Highlights
Fresh and delicious ingredients
Stylish and exciting ambiance
Excellent service
Italian-influenced menu
Noise level could improve

Indaco is a true gem in Downtown Greenville, where nostalgia meets contemporary flair. The moment I walked in, I was enveloped by a stylish ambiance that sets the stage for a delightful dining experience. The playful decor made me feel right at home. As I browsed the Italian-influenced menu, I couldn't help but appreciate their commitment to using fresh and delicious ingredients.

I opted for their signature pizza—each bite transported me to a rustic Italian kitchen. The crust was perfectly charred, showcasing that coveted balance of crunch and chewiness. Topped with vibrant flavors and quality toppings, it was a wonderful harmony that danced on my palate. The service was commendable, with attentive staff that made me feel valued without being intrusive.

One thing to note is that the noise level during peak hours could be a tad overwhelming, but the excitement in the air only added to its lively charm. Overall, Indaco delivers a delightful pizza experience that stands out in Downtown Greenville. If you're on the hunt for a pizza that combines traditional flavors with a modern twist, Indaco should definitely be on your must-visit list! 🍕✨

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D'Allesandro's Pizza

Highlights
Delicious Mushroom Madness
Amazing crispy crust
Highly recommended
Perfect pizza spot vibes
Local favorite for pickup

Review of D'Allesandro's Pizza

Stepping into D'Allesandro's Pizza, I immediately felt the buzz of local energy. The inviting aroma wafted through the air, whispering promises of cheesy goodness. I couldn't resist trying their signature Mushroom Madness, a dish that surely lives up to its name. Each bite was a delightful adventure, perfectly balancing the earthiness of mushrooms with a rich, savory sauce.

One of the standout features of this pie is its amazing crispy crust, which provides a satisfying snap with each delectable slice. So many pizzerias miss the mark with their crust, but D'Allesandro’s has truly nailed it. I sat down to enjoy my pizza amidst the lively chatter of fellow patrons, making it the perfect pizza spot for both a casual outing and a cozy night in.

With a genuine dedication to quality, it’s no surprise that D'Allesandro’s is a local favorite for pickup. Whether you're an avid pizza lover or just someone looking to treat yourself, I'd highly recommend stopping by. Your taste buds will thank you! D'Allesandro's is a slice of pizza heaven right in the heart of downtown.

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Jianna

Highlights
Creative Menu Options
Exceptional Service
Delicious Pasta Specials
Complimentary Celebrations
Fresh and Flavorful Ingredients

Jianna truly delivers an extraordinary dining experience nestled in the heart of Downtown Greenville. Walking into this charming eatery, you’re greeted with a warm ambiance and delightful aromas that promise something special. What instantly caught my attention was their creative menu options—the pizza selection boasts unique toppings like speck and truffle oil, elevating the traditional idea of pizza to a gourmet experience.

As I settled in, the exceptional service from the staff was superb, reflecting their commitment to ensuring each guest feels like royalty. Their friendly demeanor made the experience both inviting and enjoyable, a sentiment that carries through the whole evening.

The pizza I chose, brimming with fresh and flavorful ingredients, left me craving more. The crust was perfectly thin and crisp, allowing the vibrant toppings to shine. While I typically come for the pizza, I couldn’t resist sampling their delicious pasta specials, which also left a lasting impression.

In addition, Jianna celebrates its patrons with complimentary treats during special occasions, adding a touch of sweetness to the overall experience. If you ever find yourself wandering through Downtown Greenville, make sure to swing by Jianna—it’s a culinary gem you won’t want to miss!

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DeMarco's Italian

Highlights
Thoughtfully designed dining experience
Chef inspired pizza and pasta
Exceptional craft cocktails
Great service and atmosphere
Phenomenal wine list

When I stepped into DeMarco's Italian, I was immediately struck by the thoughtfully designed dining experience. The warm ambiance sets the perfect stage for an Italian feast. I chose to indulge in their chef-inspired pizza, and let me tell you, it did not disappoint! Each bite was a revelation, bursting with flavor and crafted with care.

What truly sets DeMarco’s apart is their commitment to quality and innovation. The crust had that delightful crunch while remaining chewy—exactly how I like it. Topped with fresh ingredients, every slice felt like a celebration. And if you're a fan of craft cocktails, their unique offerings will elevate your meal to a whole new level.

The service was impeccable, striking the perfect balance between attentive and relaxed, making me feel right at home. To top it all off, their phenomenal wine list pairs beautifully with the rich flavors of the food. If you’re looking for a slice of heaven in Downtown Greenville, DeMarco's Italian is where you’ll want to be! Overall, this gem is a must-visit for any pizza lover. 🍕

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Gather GVL

Highlights
Outdoor food hall experience
Colorful and inviting atmosphere
Variety of food vendors
Fun for groups and families
Reasonable prices and portions

Gather GVL Review

On my quest to uncover the best pizza in Downtown Greenville, I stumbled upon Gather GVL, a delightful outdoor food hall that brims with vibrant energy. As soon as I stepped into this bustling spot, I was greeted by a colorful atmosphere that felt like a festival of flavors. The diverse array of food vendors means there's something for everyone, but naturally, my focus was on the pizza!

I settled on a mouthwatering Margherita pizza, a classic that can make or break a pizzeria in my book. The crust was perfectly crispy yet chewy, providing a delicious foundation for the vibrant, fresh ingredients piled atop it. The savory tomato sauce paired harmoniously with the mozzarella, and the basil added a refreshing touch that made every bite a joy.

What truly sets Gather GVL apart is the ability to enjoy pizza in a lively outdoor setting—perfect for groups or families. It’s a feast for the senses, with the lively buzz of conversation and laughter echoing around me. Plus, you can’t beat the reasonable prices for such sizeable portions! If you're searching for a pizza that combines quality with a fun dining experience, Gather GVL surely rises to the top. 🍕

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Belladina's Pizzeria of Greenville

Stepping into Belladina's Pizzeria of Greenville feels like a warm hug from Grandma. The aroma of baking pizza dances around, tempting your senses. I indulged in their signature Margherita, where fresh basil, rich mozzarella, and a tangy sauce unite perfectly atop a crispy, yet chewy crust. Each bite was a delightful explosion of flavor! The cozy atmosphere is ideal for both intimate dinners and friendly gatherings. Plus, their staff exudes charisma, making the experience all the more enjoyable. For anyone searching for a slice of heaven in Downtown Greenville, Belladina's is a must-try that will leave you smiling. 🍕

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Antonino Bertolo's Pizza & Wine Bar

Stepping into Antonino Bertolo's Pizza & Wine Bar feels like a cozy hug from Italy! The wood-fired pizzas here are a revelation, boasting a perfectly charred crust that’s both crispy and chewy. I savored the Margherita, topped with fresh basil and exquisite mozzarella that melted like a dream. The ambiance is warm and inviting, ideal for a casual evening or a special date night. Pair it with one of their thoughtfully curated wines for a truly delightful experience. If you’re seeking pizza that resonates with passion, look no further than Bertolo's—a true gem in Downtown Greenville! 🍕✨

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Sidewall Pizza Company

My visit to Sidewall Pizza Company was nothing short of delightful! This gem in Downtown Greenville serves up a perfect blend of crispy crust and fresh, imaginative toppings. I savored the Sausage & Peppers pizza, where savory sausage danced harmoniously with vibrant bell peppers. The ambiance is a cozy mix of rustic charm and lively energy, making it a great spot for gatherings. Each bite was a celebration of flavors, reminding me why pizza is a beloved classic. If you're craving a slice that's both comforting and exciting, Sidewall is a must-try on your pizza pilgrimage!

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Trio - A Brick Oven Cafe

Trio - A Brick Oven Cafe is a delightful gem in Downtown Greenville that brings a touch of authentic Italian charm. Their brick oven pizzas are a revelation; each bite is a harmonious blend of fresh ingredients and perfectly charred crust. I savored the Margherita, where the simplicity of tomatoes, basil, and mozzarella sang in unison. The inviting atmosphere complemented the exquisite flavors, making it a perfect spot for a cozy meal. If you’re searching for pizza that embraces both tradition and creativity, look no further—Trio is a must-try destination for any pizza lover! 🍕✨

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Coastal Crust Greenville

At Coastal Crust Greenville, I discovered a delightful fusion of flavors that transports you straight to a coastal paradise. Their wood-fired pizzas boast a perfectly crispy crust, while the toppings are as fresh as the ocean breeze. I indulged in the Margherita, topped with vibrant basil and rich mozzarella that danced on my palate. The ambiance, with its sun-kissed decor, invites you to unwind and savor every slice. If you're seeking a slice of heaven in Downtown Greenville, this spot is a must-visit! Perfect for casual dining or a date night, Coastal Crust truly delivers a memorable pizza experience.

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