Myrtle Beach's Best Italian Sub [Updated 2026]

Myrtle Beach's Best Italian Sub [Updated 2026]
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After tasting my way through 12 of the top locations in town, I can confidently say that the quest for the best Italian sub is no small feat. Each bite brought me closer to understanding the heart and soul of these delicious sandwiches—layers of savory meats, melty cheeses, and that perfect crunch from fresh veggies.

You might wonder why you should trust my palate. Well, I’ve been devouring Italian subs (and plenty of other mouthwatering eats) for years, and I’m passionate about sharing only the best with fellow food lovers. So, grab a seat, and let’s dive into the top contenders that are sure to satisfy your cravings in Myrtle Beach!


Cafe Vincenzo's

Cafe Vincenzo's
🗺️ 7710 N Kings Hwy, Myrtle Beach, SC 29572
☎️ 843-977-4992
🌐 Website
Sunday: 11:30 AM–10 PM
Monday: 11:30 AM–10 PM
Tuesday: 11:30 AM–10 PM
Wednesday: 11:30 AM–10 PM
Thursday: 11:30 AM–10 PM
Friday: Closed
Saturday: 11:30 AM–12 AM
Highlights
Exceptional atmosphere
Modern and clean vibe
Fabulous Italian food
Delicious bread
Slightly confusing layout

When I first stepped into Cafe Vincenzo's, the atmosphere welcomed me with its vibrant decor and modern, clean vibe. The cozy ambiance certainly set the stage for what I hoped would be an exquisite dining experience.

Now, onto the star of the show: the Italian sub! This masterpiece was crafted with freshly sliced meats that danced on my palate. The bread? Absolutely divine! It had just the right amount of crunch on the outside while staying soft and chewy within. Each bite was a delightful journey through layers of flavor — from the zesty pepperoncini to the aromatic basil and tangy vinaigrette; it was nothing short of culinary magic.

However, I must admit that the restaurant layout caused a bit of confusion during my visit. I felt like I was in a charming labyrinth, trying to navigate my way to the counter, but hey, a little adventure never hurt anyone!

In conclusion, if you're in the mood for a truly sensational Italian sub in Myrtle Beach, look no further than Cafe Vincenzo's. With vibrant flavors and a welcoming atmosphere, it's a delight that you won’t want to miss.

You might also want to check out the best italian food in Columbia.

Villa Romana Italian Restaurant

Villa Romana Italian Restaurant
🗺️ 707 S Kings, State Rte, Myrtle Beach, SC 29577
☎️ 843-448-4990
🌐 Website
Sunday: 4:30–8:30 PM
Monday: 4:30–8:30 PM
Tuesday: 4:30–8:30 PM
Wednesday: 4:30–8:30 PM
Thursday: 4:30–8:30 PM
Friday: 4:30–8:30 PM
Saturday: 4:30–8:30 PM
Highlights
Warm and inviting environment
Professional and friendly staff
Authentic, fresh Italian food
Abundance of menu choices
A gem in Myrtle Beach

Villa Romana Italian Restaurant truly captures the essence of Italy right here in Myrtle Beach! Walking through the doors, I was instantly enveloped in a warm and inviting atmosphere that felt like a home away from home. The professional and friendly staff greeted me with genuine smiles, setting the tone for a delightful meal.

Now, let’s get to the star of the show: the Italian sub. When it arrived, I could hardly contain my excitement. Packed with authentic, fresh ingredients, each bite burst with the flavors of Italy. The bread was perfectly toasted, providing a crispy exterior that beautifully contrasted with the hearty fillings. The abundance of menu choices at Villa Romana makes every visit a new adventure, and I must admit, this sub might just be my go-to from now on!

This hidden gem in Myrtle Beach is more than just a place to grab a bite; it’s a culinary experience that leaves you yearning for more. If you’re on the quest for the best Italian sub in town, look no further than Villa Romana. I can’t wait to revisit and explore more of their delectable offerings!

You might also want to check out the best breakfast restaurants in Charleston.

Luigi's Trattoria

Luigi's Trattoria
🗺️ 503 61st Ave N, Myrtle Beach, SC 29577
☎️ 843-497-7080
🌐 Website
Sunday: Closed
Monday: 4–10 PM
Tuesday: 4–10 PM
Wednesday: 4–10 PM
Thursday: 4–10 PM
Friday: 4–10 PM
Saturday: 4–10 PM
Highlights
Freshly made sauces
Excellent quality dishes
Exceptional service
Outstanding gluten-free options
Highly recommended wine

When I stepped into Luigi's Trattoria, a delightful aroma enveloped me, seamlessly blending the scent of freshly made sauces with the harmony of charming Italian ambience. As a connoisseur of italian subs, I couldn’t resist the temptation to try their prized creation.

The Italian sub arrived in all its glory, generously loaded with the finest salami, capicola, and provolone, all nestled between perfectly baked bread that had a subtle crunch. But what truly set this sub apart was the house-made dressing, a zesty concoction that danced on my palate, accentuating the quality of the ingredients.

The service was equally impressive—warm, friendly, and quick to recommend their exceptional wine pairings, making my meal feel like a true Italian feast. I also noticed their commitment to inclusivity with outstanding gluten-free options, ensuring everyone can enjoy their delicious offerings.

I left Luigi's Trattoria with a satisfied palate and a smile on my face, convinced that they serve one of the best italian subs in Myrtle Beach. If you find yourself in town, make sure this gem is on your list!

You might also want to check out the best restaurants in Spartanburg.

Portofino Italian Kitchen & Wine Bar

Portofino Italian Kitchen & Wine Bar
🗺️ 9734 N Kings Hwy, Myrtle Beach, SC 29572
☎️ 843-712-1029
🌐 Website
Sunday: Closed
Monday: 5–9 PM
Tuesday: 5–9 PM
Wednesday: 5–9 PM
Thursday: 5–9 PM
Friday: 5–9:30 PM
Saturday: 5–9:30 PM
Highlights
Quaint and cozy atmosphere
Impeccable service
Delicious homemade dressing
Outstanding fresh seafood
Perfectly balanced cocktails

As soon as I stepped into Portofino Italian Kitchen & Wine Bar, I was greeted by a cozy, inviting atmosphere that felt like a warm embrace. The staff delivered impeccable service, ensuring I was comfortable and ready for a culinary adventure.

Now, onto the star of my visit: the Italian sub. This wasn’t just any ordinary sandwich; the ingredients were fresh and vibrant, with each layer adding to the symphony of flavors. My sub was generously stuffed with succulent meats and delicious cheeses, harmoniously complemented by their homemade dressing—a secret recipe that truly elevated the experience.

I savored every bite, appreciating the way the bread cradled the fillings without overpowering them. Each nibble transported me to Italy, thanks to the chef's perfect balance of flavors. To wash it down, I indulged in one of their outstanding fresh cocktails, which was an exquisite pairing with the sub.

Overall, Portofino captured my heart not just with their incredible Italian sub but also with their charming ambiance. If you find yourself in Myrtle Beach, this is one stop you won’t want to miss for an unforgettable Italian feast.

You might also want to check out the best pizza in Myrtle Beach.

Toscana Italian Kitchen

Toscana Italian Kitchen
🗺️ 2703 N Kings Hwy, Myrtle Beach, SC 29577
☎️ 843-712-2699
🌐 Website
Sunday: 4–11 PM
Monday: 4–11 PM
Tuesday: 4–11 PM
Wednesday: 4–11 PM
Thursday: 4–11 PM
Friday: 4–11 PM
Saturday: 4–11 PM
Highlights
Amazing customer service
Authentic Italian cuisine
Family-owned and operated
Delicious homemade pasta
Memorable dining experience

Toscana Italian Kitchen in Myrtle Beach is a delightful gem that promises an unforgettable dining experience. As soon as I walked through the door, I was greeted with amazing customer service that made me feel right at home. The atmosphere had that authentic Italian charm—perfect for anyone looking to enjoy a slice of Italy in South Carolina.

Now, let's talk about the Italian sub! It’s absolutely delicious—freshly prepared with high-quality ingredients that leap off the plate. The bread is perfectly crispy yet soft enough to hug the generous fillings of seasoned meats and cheeses. Topped with a zesty dressing and accompanied by vibrant, crunchy veggies, every bite is a delightful explosion of flavor.

Being a family-owned establishment, Toscana genuinely embodies the spirit of Italian culinary tradition. It’s evident that they care deeply about their craft. After indulging in their homemade pasta, I can confidently say that this place is a must-visit. Whether you're a local or just passing through, make sure to stop by and treat yourself to an Italian sub that will linger in your memory long after the last bite!

You might also want to check out the best pizza in North Myrtle Beach.

Gios Italian Kitchen Myrtle Beach

Gios Italian Kitchen Myrtle Beach
🗺️ 7915 N Kings Hwy, Myrtle Beach, SC 29572
☎️ 843-712-2238
🌐 Website
Sunday: 4:30–9 PM
Monday: 4:30–9 PM
Tuesday: 4:30–9 PM
Wednesday: 4:30–9 PM
Thursday: 4:30–9 PM
Friday: 4:30–10 PM
Saturday: 4:30–10 PM
Highlights
Delicious Italian Cuisine
Exceptional Waitstaff
Cozy and Welcoming Atmosphere
Spot-on Menu Recommendations
Unforgettable Dining Experience

Gios Italian Kitchen Myrtle Beach truly stole my heart with their rendition of the classic Italian sub! As I walked through the door, I was greeted by a cozy ambiance, making me feel instantly at home. The waitstaff were exceptionally attentive, guiding me through the delicious menu with recommendations that made my mouth water.

When I took my first bite of the Italian sub, the explosion of flavors left me utterly speechless. The freshly baked bread, with just the right level of crunch, cradled layers of premium meats and cheeses that danced together in perfect harmony. Each ingredient seemed to tell a story, with the zesty dressing tying it all together.

What impressed me more was how Gios captured the essence of Italian cuisine while keeping it playful. The artistry in presentation matched the culinary mastery at play. It wasn't just a meal; it was an unforgettable dining experience that made me feel immersed in Italian culture right here in Myrtle Beach.

If you're on the hunt for the best Italian sub, do yourself a favor and visit Gios Italian Kitchen. Trust me, your taste buds will thank you!

You might also want to check out the best cafe in Charleston.

Kaminsky's Deli

Kaminsky's Deli
🗺️ 7223 N Kings Hwy Ste 1, Myrtle Beach, SC 29572
☎️ 843-213-1261
🌐 Website
Sunday: Closed
Monday: 10 AM–3 PM
Tuesday: 10 AM–6 PM
Wednesday: 10 AM–6 PM
Thursday: 10 AM–6 PM
Friday: 10 AM–6 PM
Saturday: 10 AM–3 PM
Highlights
Well-prepared, piled-high meat
Friendly and attentive service
Unique and delightful specials
Pleasant surprise at lunch
Great first-time experience

Review of Kaminsky's Deli: The Italian Sub Triumph

Stepping into Kaminsky's Deli felt like a warm embrace from an old friend. The aroma of freshly baked bread and zesty Italian meats immediately transported me. I went in armed with the ambition to find the best Italian sub in Myrtle Beach, and boy, did Kaminsky’s deliver!

What struck me first was the sheer generosity of the sub. The meats were piled high with a delightful variety—salami, capicola, and provolone danced beautifully together. Each bite was a flavor explosion, and I savored the artful layering.

The friendly and attentive service only added to the experience, ensuring that my lunch was both delicious and enjoyable. I even found myself a little surprised by their unique specials; it’s refreshing to discover some creativity alongside such a beloved classic.

As I polished off my sub, I couldn’t help but smile. My first visit was nothing short of a culinary adventure. With its scrumptious offerings and welcoming atmosphere, I can confidently say that Kaminsky’s Deli deserves a top spot in the search for the best Italian sub in Myrtle Beach. Trust me, your taste buds will thank you!

You might also want to check out the best breakfast in North Myrtle Beach.

Quagliata Brothers Italian Deli

Quagliata Brothers Italian Deli
🗺️ 4999 Carolina Forest Blvd, Myrtle Beach, SC 29579
☎️ 843-903-1810
🌐 Website
Sunday: 8 AM–2 PM
Monday: 7 AM–6 PM
Tuesday: 7 AM–6 PM
Wednesday: 7 AM–6 PM
Thursday: 7 AM–6 PM
Friday: 7 AM–6 PM
Saturday: 7 AM–5 PM

Tucked away in the heart of Myrtle Beach, Quagliata Brothers Italian Deli is a treasure for sub lovers! The Italian sub here is a symphony of flavors, featuring freshly sliced meats, vibrant vegetables, and a drizzle of zesty oil that dances on your palate. The bread? Simply perfection—crispy on the outside, yet soft within. Each bite transports you to the vibrant streets of Italy. The friendly staff adds to the charm, always ready with a smile and a recommendation. If you’re on the hunt for an unforgettable Italian sub experience, do not miss this gem!

You might also want to check out the best ice cream in Myrtle Beach.

Toffino's Italian Bakery Deli Pizzeria

Toffino's Italian Bakery Deli Pizzeria
🗺️ 550 Farrow Pkwy, Myrtle Beach, SC 29577
☎️ 843-477-1598
🌐 Website
Sunday: Closed
Monday: Closed
Tuesday: 11 AM–9 PM
Wednesday: 11 AM–9 PM
Thursday: 11 AM–9 PM
Friday: 11 AM–9 PM
Saturday: 11 AM–9 PM

Tucked away in the heart of Myrtle Beach, Toffino's Italian Bakery Deli Pizzeria dazzled my taste buds with its mouthwatering Italian sub. The crusty bread cradled layers of savory meats, fresh veggies, and a zesty dressing that danced on my palate. Each bite was a whimsical adventure that transported me straight to Italy. The ambiance, a perfect blend of cozy and lively, only enhanced the experience. If you’re craving an authentic Italian sub that packs a punch, look no further. Toffino's is a must-visit for anyone in search of a delightful culinary escape. Buon appetito!

You might also want to check out the best burgers in Greenville.

DeVeglio's Fresh Pasta Italian Market

DeVeglio's Fresh Pasta Italian Market
🗺️ 1550 Farrow Pkwy Suite C, Myrtle Beach, SC 29577
☎️ 843-839-5955
🌐 Website
Sunday: 10 AM–3 PM
Monday: 10 AM–6:30 PM
Tuesday: 10 AM–6:30 PM
Wednesday: 10 AM–6:30 PM
Thursday: 10 AM–6:30 PM
Friday: 10 AM–6:30 PM
Saturday: 10 AM–6:30 PM

At DeVeglio's Fresh Pasta Italian Market, I was delighted by their Italian sub, a true treat for the senses. The bread, a perfectly crusty yet soft Italian hoagie, cradled a sumptuous blend of sliced meats—salami, ham, and capicola—each layer bursting with flavor. The freshly sliced provolone added a creamy richness, while their homemade Italian dressing elevated the whole masterpiece. A touch of fresh veggies gave it that garden-fresh crunch. Overall, this sub is not just a meal; it's an experience that transports you straight to Italy! If you're craving authenticity, DeVeglio's is the place to be!

You might also want to check out the best hamburger in Greenville.

Manny's Deli & Subs

Manny's Deli & Subs
🗺️ 5702 S Kings Hwy, Myrtle Beach, SC 29575
☎️ 843-946-6817
Sunday: 11 AM–4 PM
Monday: 11 AM–8 PM
Tuesday: 11 AM–8 PM
Wednesday: 11 AM–8 PM
Thursday: 11 AM–8 PM
Friday: 11 AM–8 PM
Saturday: 11 AM–8 PM

Upon stepping into Manny's Deli & Subs, I was immediately enveloped in the rich aromas of freshly baked bread and savory meats. Their Italian sub is a true celebration of flavors—layered with expertly sliced salami, pepperoni, and provolone, all drizzled with a tangy vinaigrette that dances on the palate. The crunch of the fresh lettuce and ripe tomatoes adds a delightful texture, while the perfectly toasted bread holds it all together. This sub is not just a meal; it’s an experience. If you find yourself in Myrtle Beach, Manny's is a must-visit for any sub enthusiast!

You might also want to check out the best restaurants in Kiawah Island.

Malibu Of Surfside Italian Restaurant

Malibu Of Surfside Italian Restaurant
🗺️ 815 Surfside Dr, Surfside Beach, SC 29575
☎️ 843-945-4948
🌐 Website
Sunday: 12–8 PM
Monday: Closed
Tuesday: 3–10 PM
Wednesday: 3–10 PM
Thursday: 3–10 PM
Friday: 3–10 PM
Saturday: 3–10 PM

At Malibu Of Surfside, the Italian sub is a delightful culinary adventure! This generous sandwich features layers of savory meats and zesty cheeses, all nestled in a perfectly toasted roll. Each bite is bursting with flavor, complemented by fresh veggies that add a satisfying crunch. The blend of spices transports your taste buds straight to Italy; it’s truly a feast! The atmosphere is casual yet inviting, making it a perfect spot for a quick lunch or a leisurely meal. If you’re in Myrtle Beach and craving an Italian sub that hits all the right notes, look no further than Malibu!

You might also want to check out the best lunch in Myrtle Beach.

Emily JohnsonE
WRITTEN BY

Emily Johnson

Emily Johnson is an avid storyteller and passionate advocate for Charleston, South Carolina, where she explores the city's rich history, vibrant culture, and hidden gems. Through her writing, she invites readers to experience the charm and beauty of the Lowcountry, one captivating article at a time.

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Food tour map
The Local's Blackbook 📓

The 48-Hour Insider Itinerary to Charleston

Join our See South Carolina newsletter and get our 48-hour insider itinerary to the top hidden spots in Charleston.

  • Custom 3-stop crawl with QR codes for easy navigation
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  • Insider timing tips: when to go to skip crowds
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Emily Johnson
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The Local's Blackbook 📓

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Join our See South Carolina newsletter and get our 48-hour insider itinerary to the top hidden spots in Charleston.