Santee's Best Restaurants [Updated 2025]

Santee's Best Restaurants [Updated 2025]
Food tour map
Charleston Secret Guide 🤫

Charleston Hot List 🔥

Get our exclusive guide to the top spots in Charleston! This guide includes:

  • Top 7 must-visit culinary destinations
  • Optimized 3-stop food tour route with a map
  • Expert insider tip for each location (when to go/what to order)
  • QR codes for easy navigation
  • More secret spots in your inbox every week

As I’ve wandered through the charming streets of Santee, I’ve tasted my way through a delightful array of flavors that this town has to offer. After countless meals and conversations with local chefs and food lovers alike, I’ve curated a list of 12 top spots that truly capture the culinary spirit of this community.

You can trust my expertise because I’m not just a critic; I’m a passionate foodie who believes that every meal tells a story. Whether it’s a cozy diner or an upscale eatery, I’ve savored it all, and I can’t wait to share these culinary tales with you. So, grab your fork and let’s dive into the delicious world of Santee’s finest restaurants!


The Lake House

The Lake House
🗺️ 5321 Dingle Pond Rd, Summerton, SC 29148
☎️ 803-478-3686
🌐 Website
Sunday: 4–9 PM
Monday: Closed
Tuesday: Closed
Wednesday: 4–9 PM
Thursday: 4–9 PM
Friday: 4–9 PM
Saturday: 4–9 PM
Highlights
Stunning Lake Marion views
Homemade desserts delight
Perfectly crispy hush puppies
Fantastic shrimp cocktail
Unique drink presentation

The Lake House in Santee has quickly become one of my favorite dining spots, and let me tell you, it’s not just about the food—although that’s a major highlight too. The stunning views of Lake Marion immediately set the stage for a delightful dining experience. Picture this: you’re seated outside, the sun dipping below the horizon, and the reflections dancing on the water—it feels like dining in a postcard!

Now, onto the food—where to begin? The crispy hush puppies were nothing short of perfection; I could’ve eaten a mountain of them. But the real star was the fantastic shrimp cocktail—the shrimp were fresh and zesty, served with a tangy cocktail sauce that had me going back for more. Don’t even get me started on the homemade desserts! The rich, velvety textures were a sweet end to a lovely meal.

I also loved the unique drink presentations; it's as if each sip was not just a drink but an experience. If you’re looking for a place where great food meets picturesque views, The Lake House is an absolute must-visit in Santee!

You might also want to check out the best restaurants in Spartanburg.

A&A Seafood Shack

A&A Seafood Shack
🗺️ 505 Bass Dr, Santee, SC 29142
☎️ 843-518-9730
🌐 Website
Sunday: Closed
Monday: 11 AM–8 PM
Tuesday: 11 AM–8 PM
Wednesday: 11 AM–8 PM
Thursday: 11 AM–9 PM
Friday: 11 AM–9 PM
Saturday: 11 AM–9 PM
Highlights
Fantastic gator bites
Flavorful red rice
Best fried seafood
Affordable kids meals
Fried shrimp and catfish

A&A Seafood Shack is a delightful gem that captures the essence of Southern dining right in the heart of Santee. Upon entering, I was immediately enamored by the rustic décor and the enticing aroma of freshly prepared seafood. I couldn't resist starting with their fantastic gator bites, which arrived perfectly crispy with just the right amount of seasoning that made my tastebuds dance.

The real star of the meal, however, was the fried shrimp and catfish. Each bite was a perfect blend of crispy batter and succulent seafood, taking me down memory lane of coastal fishing trips. Accompanying this feast was their flavorful red rice, which served as the ideal sidekick, elevating the overall experience.

What pleasantly surprised me was the affordability of their kids’ meals. It's refreshing to find a place that caters so well to families without breaking the bank!

For any seafood lover, A&A Seafood Shack in Santee is a must-try eatery that promises a culinary adventure with a playful atmosphere. Whether you're in the mood for a casual family dinner or a chat over delicious bites, this Shack delivers wholesome goodness every time!

You might also want to check out the best restaurants in Kiawah Island.

Thai House Restaurant

Thai House Restaurant
🗺️ 9086 Old Number Six Hwy, Santee, SC 29142
☎️ 803-854-9060
🌐 Website
Sunday: 12–9 PM
Monday: 11 AM–3 PM
Monday: 4–9 PM
Tuesday: 11 AM–3 PM
Tuesday: 4–9 PM
Wednesday: 11 AM–3 PM
Wednesday: 4–9 PM
Thursday: 11 AM–3 PM
Thursday: 4–9 PM
Friday: 11 AM–3 PM
Friday: 4–9:30 PM
Saturday: 12–9:30 PM
Highlights
Incredibly flavorful cuisine
Outstanding service from staff
Charming roadside location
Quality food exceeding expectations
Delicious Thai fried chicken

Thai House Restaurant is a delightful gem nestled in the heart of Santee, and I must say, it truly deserves a spotlight in my exploration of the best local eateries. Upon entering, I was greeted by a warm ambiance and outstanding service from the staff, whose friendly demeanor set the tone for an enjoyable meal.

The real star here, though, is the food. Each dish bursts with incredible flavor, showcasing the rich and diverse palette that Thai cuisine has to offer. I couldn't resist trying the Thai fried chicken, and let me tell you, it didn’t disappoint! The crispy exterior paired with its succulent meat was nothing short of perfection and exceeded all my expectations.

Located right off the road, the charming setting of the restaurant adds to its allure, inviting diners to indulge in a little slice of Thailand without ever leaving Santee. Whether you're a seasoned Thai food lover or a curious newcomer, Thai House promises a culinary adventure that tantalizes the taste buds. If you're in the area, make sure to stop by—your palate will thank you!

You might also want to check out the best restaurants in North Augusta.

Craig's Deli

Craig's Deli
🗺️ 9083 Old Number Six Hwy, Santee, SC 29142
☎️ 803-854-4601
🌐 Website
Sunday: 9 AM–6 PM
Monday: 9 AM–6 PM
Tuesday: 9 AM–6 PM
Wednesday: 9 AM–6 PM
Thursday: 9 AM–6 PM
Friday: 9 AM–6 PM
Saturday: 9 AM–6 PM
Highlights
Delicious Corned Beef
Quick, Friendly Service
Clean and Inviting Atmosphere
Great Alternative to Fast Food
Ideal Stop for Travelers

Craig's Deli is the kind of place that instantly feels like a warm hug on a chilly day. As I stepped inside, I was greeted by quick, friendly service that set the tone for an enjoyable visit. The ambiance strikes the perfect balance between clean and inviting—perfect for a casual meal or a quick bite before hitting the road.

Now, let's talk about that delicious corned beef! It practically melts in your mouth and is far superior to the typical fast food fare one might consider when pressed for time. Each bite bursts with flavor and is complemented by fresh bread that holds everything together without falling apart.

As a traveler looking for a good meal, I appreciated that Craig's Deli is a fabulous alternative to greasy takeout. Ideal for lunch or a hearty snack, it’s a must-visit spot when prowling through Santee.

In short, if you’re on the hunt for a delightful dining experience that won't break the bank or your sense of adventure, Craig's Deli deserves a spot on your itinerary. I left with a full belly and a smile on my face, which is all one can ask for, right?

You might also want to check out the best restaurants in Gaffney.

Armando’s Mexican Restaurant

Armando’s Mexican Restaurant
🗺️ 9134 Old, SC-6, Santee, SC 29142
☎️ 803-854-9126
🌐 Website
Sunday: 12–10 PM
Monday: 11 AM–10 PM
Tuesday: 11 AM–10 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–10 PM
Saturday: 12–10 PM
Highlights
Efficient service
Tasty food offerings
Fun atmosphere
Great drink specials
Sports viewing options

Armando’s Mexican Restaurant is a gem that brings the flavors of Mexico right to Santee’s vibrant heart. As I walked through the doors, the fun atmosphere instantly enveloped me—a lively mix of colorful decor and friendly chatter set the stage for what promised to be a delightful evening.

From the outset, the efficient service was impressive. Our server greeted us with warm smiles and had a knack for knowing just when to check in, making me feel prioritized without feeling rushed. When it came to the food, each dish was a testament to the restaurant's commitment to tasteful offerings. I indulged in their signature tacos and was thrilled by the burst of flavors, perfectly complemented by their house-made salsas.

One can’t forget the great drink specials—the margaritas were refreshingly bold, making them the perfect pairing with my meal. If you’re a sports enthusiast, the ample TV screens ensure you won’t miss a play while munching on your favorites. In short, Armando’s is a delightful dining experience that should be on every food lover’s list in Santee!

You might also want to check out the best restaurants in Irmo.

Captain's Quarters Seafood and Steak

Captain's Quarters Seafood and Steak
🗺️ 9053 Old Number Six Hwy, Santee, SC 29142
☎️ 803-854-4695
🌐 Website
Sunday: Closed
Monday: Closed
Tuesday: 5–9 PM
Wednesday: 5–9 PM
Thursday: 5–9 PM
Friday: 5–9 PM
Saturday: 5–9 PM

Captain's Quarters Seafood and Steak is a delightful find in Santee that perfectly balances charm and culinary excellence. As I settled in, I was greeted by the tantalizing aromas wafting from the kitchen. My plate of succulent shrimp scampi was a standout, bursting with flavor and perfectly cooked. The cozy atmosphere added to the overall experience, making it ideal for a romantic dinner or a family gathering. Don't miss their mouthwatering steaks—they’re cooked to perfection! With friendly service and a menu that caters to all seafood lovers, this spot is truly a gem. Come for the food, stay for the experience!

You might also want to check out the best restaurants in Hartsville.

Clark's Restaurant

Clark's Restaurant
🗺️ 114 Bradford Blvd, Santee, SC 29142
☎️ 803-854-2101
🌐 Website
Sunday: 7 AM–9 PM
Monday: 7 AM–9 PM
Tuesday: 7 AM–9 PM
Wednesday: 7 AM–9 PM
Thursday: 7 AM–9 PM
Friday: 7 AM–9 PM
Saturday: 7 AM–9 PM

Clark's Restaurant is a delightful culinary gem in Santee that truly captures the essence of comfort food with a twist. My visit was a feast for the senses—the aromas wafting from the open kitchen ignited an irresistible appetite. I savored the classic meatloaf, which was perfectly seasoned and smothered in a savory glaze. The sides? Oh, don’t even get me started—the mashed potatoes felt like a warm hug. The atmosphere was inviting, with friendly staff who genuinely make you feel at home. If you’re in Santee, skip the ordinary and indulge in Clark’s; it’s a taste bud party you won’t want to miss!

You might also want to check out the best restaurants in Boiling Springs.

Santee Steak & Seafood

Santee Steak & Seafood
🗺️ 9135 Old Number Six Hwy Suite A, Santee, SC 29142
☎️ 803-854-9919
Sunday: 4–9 PM
Monday: Closed
Tuesday: 5–9 PM
Wednesday: 5–9 PM
Thursday: 5–9 PM
Friday: 5–10 PM
Saturday: 5–10 PM

Santee Steak & Seafood is a delightful culinary oasis that’s a must-visit! As I stepped in, the warm ambiance enveloped me, and a friendly staff greeted me with a smile. I indulged in a juicy steak cooked to perfection—each bite was a celebration of flavor. The seafood options were equally enticing; the grilled salmon danced on my palate with zest! Don’t miss their signature sides, which elevate the meal to another level. Whether you're there for a special occasion or a casual dinner, this gem is a fantastic choice. Santee Steak & Seafood is definitely a taste of paradise in Santee!

You might also want to check out the best restaurants in Goose Creek.

Santee Seafood Bistro

Santee Seafood Bistro
🗺️ 648 Bass Dr, Santee, SC 29142
☎️ 803-854-4840
🌐 Website
Sunday: 11:30 AM–4 PM
Monday: Closed
Tuesday: 11:30 AM–8:30 PM
Wednesday: 11:30 AM–8:30 PM
Thursday: 11:30 AM–8:30 PM
Friday: 11:30 AM–8:30 PM
Saturday: 11:30 AM–8:30 PM

I recently had the pleasure of dining at Santee Seafood Bistro, and it was an adventure for my taste buds! The fresh catch is a highlight, with their fish tacos bursting with flavor and topped with a zesty mango salsa that danced on my palate. The ambiance is cozy yet vibrant, perfect for a casual night out. Don't miss their signature clam chowder—it's like a warm hug in a bowl! Whether you're a seafood aficionado or just looking for a delightful meal, this spot is definitely worth a visit. Santee Seafood Bistro has quickly become one of my favorites in town!

You might also want to check out the best restaurants in Garden City.

The Oasis Bar & Grill

The Oasis Bar & Grill
🗺️ 8101 Old Number Six Hwy, Santee, SC 29142
☎️ 803-854-4321
🌐 Website
Sunday: Closed
Monday: Closed
Tuesday: 2–8 PM
Wednesday: 2–10 PM
Thursday: 2–11 PM
Friday: 2 PM–1 AM
Saturday: 2 PM–12 AM

Nestled in the heart of Santee, The Oasis Bar & Grill is a delightful retreat that promises great food and an inviting atmosphere. From the moment I stepped in, the vibrant decor and friendly staff set the stage for a memorable dining experience. The menu boasts a range of delectable options, but the signature burgers stole the show with their juicy, flavorful patties and fresh toppings. Pair your meal with one of their craft cocktails, and you’re in for a treat! Whether you’re catching a game or relaxing with friends, The Oasis is the perfect spot to unwind and indulge.

You might also want to check out the best restaurants in Lancaster.

Cork and Barrel

Cork and Barrel
🗺️ 190 Plaza Circle Ste A, Santee, SC 29142
☎️ 803-857-2920
🌐 Website
Sunday: 4–9 PM
Monday: 4–9 PM
Tuesday: 4–9 PM
Wednesday: 4–9 PM
Thursday: 4–10 PM
Friday: 4–10 PM
Saturday: 4–10 PM

At Cork and Barrel, I was whisked away on a delightful culinary journey! The welcoming atmosphere immediately enveloped me, and the artfully curated wine list set the stage for a perfect evening. I savored every bite of the seasonal dishes that brilliantly showcased fresh, local ingredients. The attention to detail in each plate was impressive, especially the succulent roasted chicken—a true standout! The staff's warmth and knowledge made every interaction a genuine pleasure. If you’re seeking an unforgettable dining experience in Santee, look no further than Cork and Barrel—where every meal feels like a celebration!

You might also want to check out the best restaurants in Moncks Corner.

Alleanas santee

Alleanas santee
🗺️ 8929 Bass Dr, Santee, SC 29142
☎️ 803-956-8474
Sunday: 12–5 PM
Monday: Closed
Tuesday: Closed
Wednesday: 2–8 PM
Thursday: 2–8 PM
Friday: 12–9 PM
Saturday: 12–9 PM

I had the pleasure of dining at Alleanas Santee, a charming gem that truly captivates the senses. The moment you step inside, you’re greeted with a warm, inviting atmosphere that sets the stage for a delightful meal. Their diverse menu features mouthwatering dishes that showcase fresh ingredients and bold flavors. I highly recommend their signature pasta, which is a delightful serenade of spices and textures. The staff exude genuine hospitality, making the experience even more enjoyable. Whether you're looking for a cozy dinner or a vibrant lunch, Alleanas is a must-visit destination in Santee that leaves you craving more!

You might also want to check out the best restaurants in Walterboro.

Emily JohnsonE
WRITTEN BY

Emily Johnson

Emily Johnson is an avid storyteller and passionate advocate for Charleston, South Carolina, where she explores the city's rich history, vibrant culture, and hidden gems. Through her writing, she invites readers to experience the charm and beauty of the Lowcountry, one captivating article at a time.Read more

Related posts

featured
2025-06-04

Manning's Best Restaurants [Updated 2025]

featured
2025-06-03

The Absolute Best Restaurants in Clinton [Updated 2025]

featured
2025-06-02

Powdersville's Best Restaurants [Updated 2025]

featured
2025-06-02

The Absolute Best Restaurants in Dillon [Updated 2025]

featured
2025-05-21

The Absolute Best Restaurants in Blythewood [Updated 2025]

featured
2025-03-10

The Absolute Best Restaurant in Greer [Updated 2025]

featured
2025-04-23

The Absolute Best New Restaurants in Columbia [Updated 2025]

featured
2025-05-13

Myrtle Beach's Best New Restaurants [Updated 2025]

Food tour map
Charleston Secret Guide 🤫

Charleston Hot List 🔥

Get our exclusive guide to the top spots in Charleston! This guide includes:

  • Top 7 must-visit culinary destinations
  • Optimized 3-stop food tour route with a map
  • Expert insider tip for each location (when to go/what to order)
  • QR codes for easy navigation
  • More secret spots in your inbox every week