Santee's Best Pizza [Updated 2026]

Santee's Best Pizza [Updated 2026]
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Whether you're a Santee local or just passing through, you know that finding the perfect slice isn’t just a quest—it’s a delicious adventure. After devouring countless pies and exploring 12 of the top pizzerias in town, I’m ready to spill the juicy details that will elevate your pizza game.

I’ve tasted everything from classic pepperoni to unique gourmet creations, and trust me, I’ve developed a nose for what makes a pizza truly great. If you’re tired of the same old takeout or just want to impress your friends at dinner, let me guide you through Santee’s pizza paradise. Get ready for a flavor journey that could change your pizza nights forever!


A&A Seafood Shack

A&A Seafood Shack
🗺️ 505 Bass Dr, Santee, SC 29142
☎️ +1843-518-9730
🌐 Website
Sunday: Closed
Monday: 11 AM–8 PM
Tuesday: 11 AM–8 PM
Wednesday: 11 AM–8 PM
Thursday: 11 AM–9 PM
Friday: 11 AM–9 PM
Saturday: 11 AM–9 PM
Highlights
Fantastic gator bites
Flavorful red rice
Best fried seafood
Affordable kids meals
Great service

When I walked into A&A Seafood Shack, I was greeted with the vibrant aromas of the sea mixed with a warm, beachy vibe. Now, I know you're probably wondering about their pizza, but let me tell you, this place is a hidden gem that goes beyond just pizza. I couldn't resist trying their fantastic gator bites, which were crispy and perfectly seasoned—they're a must-try for the adventurous.

While the menu offers a variety of seafood delights, their pizza surprised me with its intriguing combination of flavors. The toppings were fresh, and the crust had a satisfying crunch that made each bite enjoyable. I paired my slice with their flavorful red rice—a delightful accompaniment that added a unique twist to the meal.

What’s more, their commitment to affordability shines through with the kids' meals, making it a great spot for family outings. The service was exceptional, with the staff being attentive yet not overbearing, enhancing the overall dining experience.

In conclusion, A&A Seafood Shack is not just about great seafood; their pizzas hold their own in this bustling pizza scene in Santee. If you're looking for a fun night out with delicious food, you won't be disappointed!

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The Lake House Restaurant

The Lake House Restaurant
🗺️ 8929 Old Number Six Hwy, Santee, SC 29142
☎️ +1803-478-3686
🌐 Website
Sunday: 4 PM–9 PM
Monday: Closed
Tuesday: Closed
Wednesday: 4 PM–9 PM
Thursday: 4 PM–9 PM
Friday: 4 PM–9 PM
Saturday: 4 PM–9 PM
Highlights
Stunning view of Lake Marion
Homemade desserts are exceptional
Perfectly crispy hush puppies
Great shrimp cocktail
Atmosphere can be negative

The Lake House Restaurant in Santee truly offers a delightful escape, both in atmosphere and flavors. Nestled alongside the shimmering waters of Lake Marion, this eatery serves up a pizza that far exceeds expectations. My experience began with the crispy crust, which was just the right balance between chewy and crunchy. I ordered their signature Lake House pizza, topped with fresh ingredients and a zesty marinara that tantalized my taste buds.

As I savored each bite, I couldn’t help but gaze out at the stunning lake view—an added bonus that elevates the meal. While I was tempted to skip dessert, the homemade offerings had me returning for just one more slice—of cake, that is! Their desserts are nothing short of exceptional, perfectly capping off my visit.

Although the atmosphere can feel a bit negative at times—perhaps due to the occasional hustle and bustle—don’t let that deter you. The Lake House is a gem for pizza lovers, blending excellent food with a stunning backdrop. If you find yourself in Santee, this is a spot you won’t want to miss for a slice (or two)! 🍕✨

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Thai House Restaurant

Thai House Restaurant
🗺️ 9086 Old Number Six Hwy, Santee, SC 29142
☎️ +1803-854-9060
🌐 Website
Sunday: 12 PM–9 PM
Monday: 11 AM–3 PM
4 PM–9 PM
Tuesday: Closed
Wednesday: 11 AM–3 PM
4 PM–9 PM
Thursday: 11 AM–3 PM
4 PM–9 PM
Friday: 11 AM–3 PM
4 PM–9:30 PM
Saturday: 12 PM–9:30 PM
Highlights
Fresh and flavorful dishes
Outstanding service by staff
Charming roadside ambiance
Good quality, exceeding expectations
Variety of dishes to explore

Thai House Restaurant is not your traditional pizza joint, but don’t let that fool you—this spot is a delightful hidden gem on the Santee dining scene. From the moment I stepped in, I was enchanted by its charming roadside ambiance. The aroma of fresh ingredients wafted through the air, promising a meal that would exceed expectations. While this cozy eatery specializes in Thai cuisine, I was surprised to find that they offered a unique twist on pizza!

I decided to try their Thai-inspired pizza, featuring tangy green curry sauce and an array of vibrant vegetables topped with fresh cilantro. The result? A fresh and flavorful dish that danced on my palate! This unexpected fusion truly showcases the creativity of the kitchen.

Adding to the experience, the outstanding service by the staff made me feel right at home. They were friendly, attentive, and eager to share their recommendations, which certainly enhanced my visit.

While many may venture here for the sumptuous Thai dishes, I can confidently say that Thai House Restaurant offers a delightful experience worth exploring, especially if you're in search of something beyond traditional pizza in Santee!

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Craig's Deli

Craig's Deli
🗺️ 9083 Old Number Six Hwy, Santee, SC 29142
☎️ +1803-854-4601
🌐 Website
Sunday: 8 AM–6 PM
Monday: 8 AM–6 PM
Tuesday: 8 AM–6 PM
Wednesday: 8 AM–6 PM
Thursday: 8 AM–6 PM
Friday: 8 AM–6 PM
Saturday: Closed
Highlights
Solid Reuben
Delicious Corned Beef
Quick, Friendly Service
Clean Restrooms
Charming Atmosphere

Ah, Craig's Deli—a delightful surprise nestled in the heart of Santee! As I stepped inside, I was greeted by a charming atmosphere that felt both cozy and inviting. These lovely folks serve more than just pizza; I couldn't resist trying their solid Reuben sandwich while I was there. The delicious corned beef was piled high, tender, and flavorful, making it clear that they know their meats well.

However, let's talk about their pizza! While it's not the primary offering, you can find hidden gems among the options. The crust is the right amount of crispy, and the toppings are always generous, using quality ingredients that sing with flavor.

What really impressed me was the quick, friendly service. The staff made me feel right at home, ensuring I had everything I needed to enjoy my meal. It’s the kind of place where you can take a moment to unwind, thanks to the clean restrooms and pleasant dining area.

So, if you're in Santee and looking to satisfy your pizza cravings with a side of some classic deli magic, Craig's Deli is definitely worth a visit. Trust me, your taste buds will thank you! 🍕✨

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Armando’s Mexican Restaurant

Armando’s Mexican Restaurant
🗺️ 9134 Old, SC-6, Santee, SC 29142
☎️ +1803-854-9126
🌐 Website
Sunday: 12 PM–10 PM
Monday: 11 AM–10 PM
Tuesday: 11 AM–10 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–10 PM
Saturday: 12 PM–10 PM
Highlights
Efficient service
Excellent food
Fun and engaging waitstaff
Tasty menu offerings
Great drink specials

Armando’s Mexican Restaurant is not just about tacos and enchiladas—it surprisingly serves up some delicious pizza too! My visit was a delightful adventure where the efficient service from the moment I stepped in truly set the tone for a great meal. The fun and engaging waitstaff made my dining experience even more memorable, adding a playful vibe that complemented the cheerful ambiance.

As I browsed the tasty menu offerings, I decided to go for their unique take on pizza. The crust was delightfully crispy, and the toppings were fresh and generous—not something you typically expect in a Mexican restaurant! Each bite was a wonderful blend of flavors, reminiscent of both Italian and Mexican cuisines, which made for a distinctive experience.

What surprised me as well were the great drink specials that paired perfectly with the meal. Enjoying a cool drink boosted the pizza’s flavors even more! Overall, I left Armando’s impressed, not just by the food but by the engaging atmosphere that makes you feel at home. For anyone looking for a fun twist on pizza in Santee, I highly recommend giving Armando’s a try!

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Thommy Mac's

Thommy Mac's
🗺️ 6322 M W Rickenbaker Rd, Summerton, SC 29148
☎️ +1803-478-7337
🌐 Website
Sunday: 12:30 PM–6 PM
Monday: Closed
Tuesday: 1 PM–12 AM
Wednesday: 12 AM–12 PM
1 PM–12 AM
Thursday: 12 AM–12 PM
1 PM–12 AM
Friday: 12 AM–12 PM
1 PM–2 AM
Saturday: 1 PM–2 AM
Highlights
Excellent burger options
Fast and friendly service
Great atmosphere and vibes
Reasonably priced menu
Outstanding appetizers

Thommy Mac's in Santee is quite the gem for pizza lovers and food enthusiasts alike! As soon as I stepped in, the vibrant atmosphere captured my attention. It has that perfect blend of casual and lively vibes, making it a great spot for a night out or a quick bite with friends.

Let's talk about the pizza — it’s a must-try! Each slice is laden with fresh toppings and gooey cheese that pulls apart irresistibly with each bite. The crust strikes a balance between crispy and chewy, which I found absolutely delightful. But wait, there’s more; Thommy Mac's doesn't stop at pizza. Their excellent burger options are equally tempting, perfect for those who want to mix things up.

What really stood out to me was the fast and friendly service. The staff was attentive and provided recommendations that didn’t disappoint. Also, I appreciated their reasonably priced menu, allowing you to indulge without breaking the bank.

Lastly, kick off your meal with their outstanding appetizers — they set the perfect tone for what’s to come. If you find yourself in Santee, don’t miss out on this culinary hotspot! 🌟

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Za's on Devine

Za's on Devine
🗺️ 2930 Devine St, Columbia, SC 29205
☎️ +1803-771-7334
🌐 Website
Sunday: Closed
Monday: 11 AM–9:30 PM
Tuesday: 11 AM–9:30 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–10 PM
Saturday: 10:30 AM–10 PM
Highlights
Delicious spinach dip
Attentive and friendly service
Plentiful outdoor seating
Quick food preparation
Generous pizza portions

Upon stepping into Za's on Devine, I was immediately charmed by the casual vibe and the spacious outdoor seating area, perfect for enjoying a pizza al fresco. Their menu boasts a variety of options, but I couldn't resist starting with their delicious spinach dip—a creamy, savory delight that set the stage for what was to come.

When my pizza arrived, I was impressed by the generous portion size. Each slice was overflowing with toppings and the crust had that ideal balance of crispy on the outside and chewy on the inside, making every bite delightful. The staff at Za's proved to be nothing short of attentive and friendly, enhancing the overall dining experience with their cheery demeanor and quick food preparation.

What stood out most was not just the quality of the pizza, but the inviting atmosphere that made me want to linger longer than usual. After all, what’s better than enjoying a delicious slice with good company under the Santee sky? I left wishing I had room for dessert! Za's on Devine is definitely a must-visit for pizza lovers looking for a taste of Santee’s finest offerings.

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Subway

Subway
🗺️ SC-6, Santee, SC 29142
☎️ +1803-854-2054
🌐 Website
Sunday: 8 AM–9 PM
Monday: 8 AM–10 PM
Tuesday: 8 AM–10 PM
Wednesday: 8 AM–10 PM
Thursday: 8 AM–10 PM
Friday: 8 AM–10 PM
Saturday: 8 AM–10 PM
Highlights
Nice and caring staff
Spotlessly clean restaurant
Consistent quality subs
Highly recommended location

Subway in Santee: A Fresh Twist on Pizza!

While I’m on the quest for the best pizza in Santee, my recent visit to Subway certainly provided an unexpected delight. Admittedly, I walked in with a slice of skepticism; after all, what could a sandwich shop know about pizza? But I was pleasantly surprised.

Upon entering, I was greeted by the nice and caring staff who exuded warmth as they took my order. The restaurant itself was a breath of fresh air—spotlessly clean and inviting, making it the perfect stop for hungry Santee locals. Although Subway's forte lies in subs, the creativity of their specialty pizzas showcases their dedication to delivering consistent quality.

Now, while the traditional pizza lovers may look elsewhere, I found their personal pizzas to be a fun and customizable option for those wanting to indulge in something different. With a variety of fresh ingredients at my disposal, crafting a unique creation became an adventure in itself!

In conclusion, if you're in Santee and looking for a break from the conventional pizza experience, don’t overlook Subway! It may just surprise you with its unique flair and fresh ingredients that keep patrons coming back for more.

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Love's Travel Stop

Love's Travel Stop
🗺️ 401 Buff Blvd, Summerton, SC 29148
☎️ +1803-488-2000
🌐 Website
Sunday: 12 AM–12 PM
Monday: 12 AM–12 PM
Tuesday: 12 AM–12 PM
Wednesday: 12 AM–12 PM
Thursday: 12 AM–12 PM
Friday: 12 AM–12 PM
Saturday: 12 AM–12 PM
Highlights
Clean facilities
Friendly staff
Safe for solo travelers
Ample parking for trucks
Fresh food options

Review of Love's Travel Stop in Santee

Upon entering Love's Travel Stop in Santee, I was greeted by an ambiance that struck the perfect balance between playful and practical. The clean facilities instantly made me feel at ease, and I couldn't help but appreciate how friendly the staff were. This spot might be a gas station, but it's surprisingly welcoming—perfect for solo travelers seeking a quick yet satisfying meal.

Now, let's discuss the pizza! I was pleasantly surprised by the assortment of fresh food options available. The pizza, though served in a casual setting, tasted like it was crafted with care. Flavors danced on my palate, with a crust that was baked to perfection—crispy on the outside and delightfully chewy on the inside. It’s the sort of pizza that you wouldn't expect from a travel stop, making it an unexpected gem.

The ample parking for trucks also adds to its charm; it's a convenient pit stop for those on the road. Overall, Love's Travel Stop is more than just a gas station—it's a delightful culinary surprise for any pizza lover passing through Santee.

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Music Man's Bar-B-Que

Music Man's Bar-B-Que
🗺️ 112 State Rd S-8-225, Moncks Corner, SC 29461
☎️ +1843-899-7675
🌐 Website
Sunday: 11 AM–2:30 PM
Monday: Closed
Tuesday: Closed
Wednesday: 11 AM–8 PM
Thursday: 11 AM–8 PM
Friday: 11 AM–8 PM
Saturday: 11 AM–8 PM
Highlights
Amazing Staff
Good Country Vibes
Decent BBQ Flavor
Variety of Menu Options
Popular Buffet Selection

Music Man's Bar-B-Que might not be the first place that springs to mind when you're hunting for pizza in Santee, but let me tell you, this hidden gem has a delightful surprise waiting for you! From the moment I walked in, the amazing staff greeted me with genuine warmth, which instantly set the stage for a great experience.

The ambiance exudes good old country vibes, making it an inviting spot for families and friends alike. While their BBQ is undeniably the star of the show, I decided to try their pizza, curious to see how it would measure up. The variety of menu options is impressive; you’ll want to explore every nook and cranny of their culinary offerings.

Now, the pizza itself? Surprisingly decent! It featured a nice blend of toppings that complemented the smoky flavors typically associated with BBQ establishments. The popular buffet selection gives you the flexibility to sample various pies, keeping things exciting.

In a town brimming with pizza choices, Music Man’s truly stands out for its unique twist on flavor and top-notch service. If you're feeling adventurous, grab a slice here and enjoy the blend of BBQ and pizza perfection!

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California Dreaming

California Dreaming
🗺️ 401 Main St, Columbia, SC 29201
☎️ +1803-254-6767
🌐 Website
Sunday: 11 AM–9 PM
Monday: 11 AM–9 PM
Tuesday: 11 AM–9 PM
Wednesday: 11 AM–9 PM
Thursday: 11 AM–9 PM
Friday: 11 AM–10 PM
Saturday: 11 AM–10 PM
Highlights
Amazing and quick service
Delicious food
Impeccable atmosphere
Beautiful woodwork
No wait, even when busy

Review of California Dreaming in Santee

When you enter California Dreaming, you’re immediately wrapped in a warm, inviting atmosphere. The stunning woodwork is just a hint of the delightful experience that awaits. Despite a bustling crowd, I was pleased to find that the service was quick and attentive, ensuring I didn’t have to wait long for my pizza fix.

Now, let's talk about the pizza! I ordered their signature pie, and let me tell you, it was a slice of heaven. The crust was perfectly crispy yet chewy, providing a wonderful foundation for vibrant toppings that burst with flavor. Every bite took me on a delightful journey that made my taste buds dance in delight.

I appreciated the overall ambiance of the restaurant; it struck a balance between cozy and lively, making it the perfect spot for a casual dinner or a fun night out with friends. It’s rare to find a place that combines excellent food with a welcoming vibe so effortlessly.

If you’re on the hunt for exceptional pizza in Santee, do yourself a favor and visit California Dreaming. You won't just enjoy a meal; you'll create a memorable experience!

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The Baked Bear

The Baked Bear
🗺️ 631 Harden St Ste C, Columbia, SC 29205
☎️ +1803-834-4004
🌐 Website
Sunday: 12 PM–10 PM
Monday: 12 PM–10 PM
Tuesday: 12 PM–10 PM
Wednesday: 12 PM–10 PM
Thursday: 12 PM–10 PM
Friday: 12 PM–10 PM
Saturday: 12 PM–10 PM
Highlights
Unique ice cream sandwiches
Customizable cookie options
Friendly and helpful staff
Delicious flavor combinations
Perfect for dessert cravings

The Baked Bear in Santee is a delightful surprise, offering a dessert twist that absolutely complements the pizza scene here. Although it’s primarily known for its ice cream sandwiches, I was thrilled to find that their atmosphere invites you to indulge in more than just savory delights. What makes this spot stand out is its customizable cookie options—imagine matching warm, gooey cookies with your favorite ice cream!

The staff were not just friendly; they were eager to help you navigate the vast assortment of delicious flavor combinations. My taste buds danced with excitement as I paired a classic chocolate chip cookie with a rich cookies-and-cream ice cream. It was the kind of decadent experience that continues to call me back for more!

Even though The Baked Bear isn't a pizzeria per se, I believe it deserves a nod in any discussion about food in Santee, especially for those who appreciate a sweet conclusion to their pizza meal. If you find yourself craving dessert after a steaming slice of pizza, this is the place to go. After all, what's better than a heavenly ice cream sandwich to top off a great day of pizza tasting?

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Emily JohnsonE
WRITTEN BY

Emily Johnson

Emily Johnson is an avid storyteller and passionate advocate for Charleston, South Carolina, where she explores the city's rich history, vibrant culture, and hidden gems. Through her writing, she invites readers to experience the charm and beauty of the Lowcountry, one captivating article at a time.

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Food tour map
The Local's Blackbook 📓

The 48-Hour Insider Itinerary to Charleston

Join our See South Carolina newsletter and get our 48-hour insider itinerary to the top hidden spots in Charleston.

  • Custom 3-stop crawl with QR codes for easy navigation
  • 5 photo-worthy hidden gems (Instagram gold)
  • Insider timing tips: when to go to skip crowds
  • Top spots in your inbox every week
Emily Johnson
Charleston Black Book
The Local's Blackbook 📓

INSIDER ITINERARY

Join our See South Carolina newsletter and get our 48-hour insider itinerary to the top hidden spots in Charleston.